Research Paper Volume 16, Issue 17 pp 12191—12208

Aging-related biomarkers for the diagnosis of Parkinson’s disease based on bioinformatics analysis and machine learning

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Figure 4. Protein-protein interaction network for the four potential diagnostic biomarkers constructed in GeneMANIA. Different colors of the network edge indicate the bioinformatics method applied: physical interaction, coexpression, predicted, colocalization, pathway, genetic interaction, and shared protein domains.