Research Paper Volume 16, Issue 13 pp 10799—10812
G-CSF promotes the development of hepatocellular carcinoma by activating the PI3K/AKT/mTOR pathway in TAM
Figure 3. Examination of G-CSF influence on SHP-2 and PI3K/AKT/mTOR pathway activity in neoplastic tissues utilizing western blotting techniques. (A) Protein bands demonstrating SHP-2, phosphorylated PI3K, total PI3K, phosphorylated AKT, total AKT, phosphorylated mTOR, and total mTOR. (B) Comparative proteinic expression levels of SHP-2, the ratio of phosphorylated to total PI3K, the ratio of phosphorylated to total AKT, and the ratio of phosphorylated to total mTOR. The P-value is less than 0.05.