Research Paper Volume 16, Issue 20 pp 13076—13103

A lactate metabolism-related gene signature to diagnose osteoarthritis based on machine learning combined with experimental validation

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Figure 6. Construction and validation of the diagnostic nomogram. (A) A nomogram was constructed to visualize the LR model. (BD) ROC analysis shows the predictive ability of the nomogram in the training (B), validation-cartilage (C), and validation-synovial (D) cohorts. (EG) Calibration analysis shows the predictive ability of the nomogram in the training (E), validation-cartilage (F), and validation-synovial (G) cohorts. (HJ) DCA analysis shows the predictive ability of the nomogram in the training (H), validation-cartilage (I), and validation-synovial (J) cohorts. Abbreviations: ROC, receiver operating characteristic; DCA, decision curve analysis; LR, logistic regression.