Research Paper Volume 16, Issue 20 pp 13076—13103
A lactate metabolism-related gene signature to diagnose osteoarthritis based on machine learning combined with experimental validation
Figure 2. Differentially-expressed lactate metabolism-related genes. (A) The schematic summary of the biological functions of lactate. (B, C) The volcano plot (B) and the heat map (C) indicated that 74 of 273 lactate metabolism-related genes were differentially expressed between the control and OA tissues. (D) The functional annotation of the 74 genes. Abbreviation: OA, osteoarthritis.