Research Paper Volume 16, Issue 9 pp 8142—8154
4-hydroxysesamin protects rat with right ventricular failure due to pulmonary hypertension by inhibiting JNK/p38 MAPK signaling
Figure 2. 4-HS protects PASMC in inflammatory stimuli and hypoxic environments. (A) EDU staining to detect changes in the proliferative capacity of treated PASMC (Scale bar, 50 μm). (B) CCK8 assay to detect changes in the proliferative capacity of PASMC after treatment with 4-HS PASMC treated with 4-HS and Anisomycin for 24 h. (C) ELISA assay to detect changes in the expression of inflammatory factors IL-1β, IL-6, IL-10, and TNF-α in PASMC treated with 4-HS in combination with Anisomycin for 24 h in LPS and hypoxia-stimulated environments.