Research Paper Volume 16, Issue 9 pp 8142—8154
4-hydroxysesamin protects rat with right ventricular failure due to pulmonary hypertension by inhibiting JNK/p38 MAPK signaling
Figure 1. Effect of Sesamin and 4-HS on the inflammatory response to PASMC cell viability. (A) 2D and 3D molecular structural formulae of 4-HS and the relative molecular mass of 4-HS. (B) CCK8 assay to detect the effect of different concentrations of 4-HS on cellular value-added after acting on PASMC for 24 h. (C) CCK8 assay to detect the effect of 4-HS on the cell viability of PASMC in inflammatory and hypoxic environments. (D) ELISA assay to detect changes in expression of inflammatory factors IL-1β, IL-6, IL-10, and TNF-α in inflammatory and hypoxic environments under 4-HS expression changes of inflammatory factors IL-1β, IL-6, IL-10, and TNF-α after 24 h of 4-HS treatment.