Research Paper Advance Articles

SHP2 mediates STAT3/STAT6 signaling pathway in TAM to inhibit proliferation and metastasis of lung adenocarcinoma

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Figure 1. Inhibition of SHP2 in TAM can promote M2 polarization and the development of lung adenocarcinoma. (A) Subcutaneous tumor assay in nude mice and data statistics; (B) Western blot detects M2 markers: the expression of CD163, CD206 and Arginase-1. N=8;**P<0.01.