Research Paper Volume 16, Issue 18 pp 12498—12509
SHP2 mediates STAT3/STAT6 signaling pathway in TAM to inhibit proliferation and metastasis of lung adenocarcinoma
Figure 1. Inhibition of SHP2 in TAM can promote M2 polarization and the development of lung adenocarcinoma. (A) Subcutaneous tumor assay in nude mice and data statistics; (B) Western blot detects M2 markers: the expression of CD163, CD206 and Arginase-1. N=8;**P<0.01.