Human umbilical cord mesenchymal stem cells promote steroid-induced osteonecrosis of the femoral head repair by improving microvascular endothelial cell function

Junwen Chen; Wenyi Jin; Changheng Zhong; Wenxiang Cai; Liangkun Huang; Jianlin Zhou; Hao Peng

doi:doi:10.18632/aging.205794

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Research Paper Volume 16, Issue 9 pp 7928—7945

Human umbilical cord mesenchymal stem cells promote steroid-induced osteonecrosis of the femoral head repair by improving microvascular endothelial cell function

Figure 7. hUCMSCs improved the migration ability and angioplasty of Dex-treated BMECs. (A) Wound healing at 0, 12, and 24 h after Dex treatment. (B) Tube formation assay at 12 h after Dex treatment. (C) Scratch closure rate in three groups. (D, E) Total length and Total branching points in three groups. The data are presented as the means ± SD (n = 3). ^*p < 0.05, ^**p < 0.01, ^***p < 0.001, compared with the Con group. ^#p < 0.05, ^##p < 0.01, ^###p < 0.001, compared with the Dex group. Scale bars: 50 μm.