Human umbilical cord mesenchymal stem cells promote steroid-induced osteonecrosis of the femoral head repair by improving microvascular endothelial cell function

Junwen Chen; Wenyi Jin; Changheng Zhong; Wenxiang Cai; Liangkun Huang; Jianlin Zhou; Hao Peng

doi:doi:10.18632/aging.205794

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Research Paper Volume 16, Issue 9 pp 7928—7945

Human umbilical cord mesenchymal stem cells promote steroid-induced osteonecrosis of the femoral head repair by improving microvascular endothelial cell function

Figure 4. scRNA-seq was used to analyze and identify different cell types and EC clusters. (A) Cell type annotation of 9 clusters. (B) The percentage of clusters and cell types in each sample was represented on a proportion chart. (C) The heat map shows the top 10 marker genes in each cluster. (D) Two-dimensional plots of UMAP dimensionality reduction of the ECs. (E) ECs signature genes embedded on t-SNE dimension reduction map. (F) Dot plot showing marker genes for ECs subtypes. (G) tSNE shows the color-coded clustering for ECs.