Human umbilical cord mesenchymal stem cells promote steroid-induced osteonecrosis of the femoral head repair by improving microvascular endothelial cell function

Junwen Chen; Wenyi Jin; Changheng Zhong; Wenxiang Cai; Liangkun Huang; Jianlin Zhou; Hao Peng

doi:doi:10.18632/aging.205794

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Research Paper Volume 16, Issue 9 pp 7928—7945

Human umbilical cord mesenchymal stem cells promote steroid-induced osteonecrosis of the femoral head repair by improving microvascular endothelial cell function

Figure 3. hUCMSCs reduced the incidence of empty lacunae and increased the number of CD31+ microvessels. (A) The bone tissues were analyzed via HE staining. (B) Immunohistochemistry staining of CD31. (C) Quantitative analysis of empty lacunae. (D) Quantitative analysis of the number of CD31+ vessels. The data are presented as the means ± SD (n = 7). ^*p < 0.05, ^**p < 0.01, ^***p < 0.001, compared with the MPS group. ^#p < 0.05, ^##p < 0.01, ^###p < 0.001, compared with the Dex group.