Figure 6 — IL21 inhibits miR-361-5p to promote MAP3K9 and further aggravate the progression of shoulder arthritis

Research Paper|Volume 16, Issue 9|pp. 7915–7927

IL21 inhibits miR-361-5p to promote MAP3K9 and further aggravate the progression of shoulder arthritis

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Figure 6.Overexpression of miR-361-5p inhibits the expression of MAP3K9, thus inhibiting the expression of MMPs in chondrocytes. (A) Protein band plots of MAP3K9, p-ERK1/2, p-NF-κB, MMP1 and MMP9. (B) Relative protein expression statistics of MAP3K9, p-ERK1/2, p-NF-κB, MMP1 and MMP9. N = 3; ^**P < 0.01, miR-NC vs. miR-mimic; ^nsP > 0.05, miR-NC+MAP3K9 OE vs. miR-mimic+MAP3K9 OE.