Research Paper Volume 16, Issue 9 pp 7915—7927

IL21 inhibits miR-361-5p to promote MAP3K9 and further aggravate the progression of shoulder arthritis

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Figure 4. IL21 promotes chondrocyte apoptosis by regulating the expression of miR-361-5p. (A) Plots of apoptosis results of HC-1 cells after co-treatment with IL21 or IL21 and miR-361-5p. (B) The apoptosis rate of HC-1 cells after co-treatment with IL21 or IL21 and miR-361-5p. N = 8; **P < 0.01, NC vs. IL21, IL21+miR-NC vs. IL21+miR-361-5p.