Research Paper Volume 16, Issue 9 pp 7818—7844
Unraveling the unfolded protein response signature: implications for tumor immune microenvironment heterogeneity and clinical prognosis in stomach cancer
Figure 15. Functional validation of IGFBP1 in AGS and MKN45 cell lines. (A) The knockdown efficiency of IGFBP1 was tested by qPCR in MKN45 and AGS cell lines. (B) The proliferation efficiency of MKN45 and AGS cell lines with IGFBP1 knockdown by CCK8 assay. (C) The proliferation efficiency of MKN45 and AGS cell lines with IGFBP1 knockdown by cell cloning formation. (D) The statistical analysis of (C). (E) The apoptosis of MKN45 and AGS cell lines with IGFBP1 knockdown. (F) The statistical analysis of (E). (G) The migration efficiency of MKN45 and AGS cell lines with IGFBP1 knockdown. (H) The statistical analysis of (G). (I) The invasion efficiency of MKN45 and AGS cell lines with IGFBP1 knockdown. (J) The statistical analysis of (I).