Research Paper Volume 16, Issue 9 pp 7752—7773

Figure 6. Effect of HOTAIR in CRC cell proliferation and migration. (A) Transcription level of HOTAIR in CRC cell lines and NCM460. (B) Transcription level of HOTAIR in HCT116 and SW480 were significantly downregulated by si-HOTAIR transfection, respectively. (C) Relative expression of HOTAIR in CRC tissues was assessed by comparing with normal samples (n = 25). (D) Cell proliferation was assessed by CCK assay. (E) Transwell assay employed to detect the migration ability of HOTAIR knockdown cells. ^*p < 0.05; ^**p < 0.01; ^***p < 0.001.