Review Volume 16, Issue 8 pp 7487—7504

Figure 3. The four most related metabolic pathways in digestive system tumors. The metabolic process of metabolites and the proteins involved in their regulation. Differentially expressed metabolites (red), unchanged metabolites (grey), regulated proteins (yellow), metabolic pathway names (blue). Abbreviations: ACY1: aminoacylase; ADSL: adenylosuccinate lyase; ADSS1: adenylosuccinate synthase 1; AGST: alanine-glyoxylate transaminase; ARG1: arginase 1; AS: asparagine synthase; ASL: argininosuccinate lyase; ASS1: argininosuccinate synthase 1; GCAT: glycine C-acetyltransferase; GLS: glutaminase; GLT1: glutamate synthase; GLUT1: glucose transporter 1; glyA: glycine hydroxymethyltransferase; GOT1L1: glutamic-oxaloacetic transaminase 1 like 1; ilvE: branched-chain amino acid aminotransferase; IL4I1: interleukin 4 induced 1; OTC: ornithine transcarbamylase; PC: pyruvate carboxylase; SDS: threonine ammonia-lyase; SCL1A5: solute carrier family 1; TDH: threonine 3-dehydrogenase.