Research Paper Volume 16, Issue 9 pp 7704—7732
Immune cell senescence and exhaustion promote the occurrence of liver metastasis in colorectal cancer by regulating epithelial-mesenchymal transition
Figure 7. In vitro experimental results. (A) Evaluation of scratch tests conducted at 24 h and 48 h following SDC1 knockdown, relative to the negative control group, with subsequent determination of wound healing percentage. (B) Assessment of scratch tests performed at 24 h and 48 h following SDC4 knockdown, relative to the negative control group, with subsequent determination of wound healing percentage. (C) Analysis of Transwell migration experiments following SDC1 knockdown, relative to the negative control group. (D) Examination of Transwell migration experiments following SDC4 knockdown, relative to the negative control group. (E) Contrasting the mRNA relative expression levels of CDH1, CDH2, and VIM following SDC1 knockdown with those of the negative control group. (F) Contrasting the mRNA relative expression levels of CDH1, CDH2, and VIM following SDC4 knockdown with those of the negative control group. (G) Contrasting the protein relative expression levels of E-cadherin, N-cadherin, and Vimentin following SDC1 or SDC4 knockdown with those of the negative control group. (*P < 0.05, **P < 0.01, ***P < 0.001).