Figure 4. Gene expression analysis comparing UV-A- and IR-induced senescent human corneal endothelial cells. (A, B) Gene ontology analysis of upregulated genes comparing (A) UV-A-induced senescent hCEnCs and non-senescent hCEnCs (control), as well as (B) IR-induced senescent hCEnCs and control. (C, D) Gene ontology analysis of down-regulated genes comparing (C) UV-A-induced senescent hCEnCs and control, as well as (D) IR-induced senescent hCEnCs and control.