Research Paper Volume 16, Issue 8 pp 7073—7100

Figure 7. The correlation between βAMRGs scores and immune cell infiltration within the three clusters was investigated. (A) The heatmap displays variations in immune cell infiltration levels across the three subgroups based on βAMRGs scores. (B) The box plot demonstrates discrepancies in immune checkpoint expression among the three subgroups. (C) The heatmap depicts the relationship between βAMRGs-associated genes and immune cell infiltration levels. (D) The plot shows the link between βAMRGs scores and immune cell infiltration levels. The size of the sphere on the right side represents the correlation strength (abs) and the color represents the corresponding p-value. (E–H) The scatter plot depicts the relationship of βAMRGs scores with 4 immune-infiltration-related substances. The βAMRGs scores were shown to have a positive link to the infiltration levels of Type I IFN Response and Type II IFN Response. The βAMRGs scores were shown to have a negative link to the infiltration levels of aDCs and Treg. (* indicates p <0.05; ** indicates p < 0.01; *** indicates p < 0.001; **** indicates p < 0.0001).