Figure 6. ROC analysis. In both GSE16561+GSE22255 (A) and GSE58294 (C) datasets, box plots were used to illustrate the expression patterns of hub genes between IS and normal samples. To determine the diagnostic performance of hub genes, we conducted ROC analysis for the GSE16561+GSE22255 (B) and GSE58294 (D) datasets. ROC, receiver operating characteristic; AUC, area under curve; FPR, false positive rate; TPR, true positive rate.