Figure 2. The cellular communication between C6 and other clusters. The circle diagrams show the high intercellular interactions concerning the number (A) and strength (B) of ligand–receptor interactions among the 22 clusters. Interactions between overexpressed ligands and receptors are shown in the bubble chart when C6 cluster cells act as the ligand (C) and receptor (D) cells, respectively. Permutation test P-values are represented by bubble size, while interaction possibilities are represented by color.