Research Paper Volume 16, Issue 3 pp 2989—3006
Minocycline alleviates LPS-induced cognitive dysfunction in mice by inhibiting the NLRP3/caspase-1 pathway
Figure 6. Minocycline suppressed NLRP3/caspase-1 pathway activation in LPS-treated BV2 cells. (A) The protocol of BV2 cell treatments. (B–F) The expressions of NLRP3, caspase-1, IL-1β, and IL-18 was determined by Western blotting assay. Data were presented as mean ± SD; n = 4; ns: statistically non-significant; *P < 0.05, **P < 0.01, ***P < 0.001 vs. control group; #P < 0.05, ##P < 0.01, ###P < 0.001 vs. LPS group.