Research Paper Volume 16, Issue 3 pp 2989—3006
Minocycline alleviates LPS-induced cognitive dysfunction in mice by inhibiting the NLRP3/caspase-1 pathway
Figure 4. Minocycline inhibited the NLRP3/Casapase-1 pathway in the hippocampus of LPS-treated mice. (A) Representative Western blot bands of NLRP3, Caspase-1, IL-1β, and IL-18, and (B–E) their statistical graphs. (F–I) The mRNA expression of NLRP3, caspase-1, IL-1β, and IL-18. Data were presented as mean ± SD, n = 5–6 mice per group; *P < 0.05, **P < 0.01, ***P < 0.001 vs. control group; #P < 0.05, ##P < 0.01, ###P < 0.001 vs. LPS group.