Research Paper Volume 16, Issue 3 pp 2989—3006

Figure 1. Minocycline improved LPS-induced learning and memory impairment in mice. (A) Schematic representation of the animal experiment. (B) The mean escape latency to the visible platform of the MWM test. (C) Numbers of platform location crossings during the probe trial test of MWM test. (D) A representative trajectory diagram of the MWM test. (E) Ratio of entering the novel arm. (F) Ratio of spending time in the novel arm. (G) A representative trajectory diagram of the Y-maze. Data were presented as mean ± SD; n = 6 mice per group. ^*P < 0.05, ^**P < 0.01, ^***P < 0.001 vs. Control group; ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 vs. LPS group.