Netrin-1 mitigates acute lung injury by preventing the activation of the Toll-like receptor 4/nuclear factor-κB (TLR4/NF-κB) signaling

Jian Su; Zhu Jian; Miao Zou; Huasheng Tong; Peng Wan

doi:doi:10.18632/aging.205527

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Research Paper Volume 16, Issue 3 pp 2978—2988

Netrin-1 mitigates acute lung injury by preventing the activation of the Toll-like receptor 4/nuclear factor-κB (TLR4/NF-κB) signaling

Figure 2. Netrin-1 improved histopathological changes and lung function in lung tissues in LPS- challenged ALI mice. (A). Histopathological changes of the lung tissue; Scale bar, 100 μm; (B). RAW (cmH₂O mL/min); (C). Cdyn (mL/cmH2O); (D). PEF (mL/S) (^††P < 0.01 vs. vehicle group; ^**P < 0.01 vs. LPS group).