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Research Paper|Volume 16, Issue 3|pp. 2789–2811
Targeting PERK-ATF4-P21 axis enhances the sensitivity of osteosarcoma HOS cells to Mppα-PDT
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Figure 9
Figure 9.The potential mechanisms of inhibiting Perk-ATF4-P21 pathway to enhance the efficacy of MPPα-PDT. Antitumor ability of Mppα-PDT is improved by inhibiting PERK signaling, which is achieved by P21 regulating autophagy.