Research Paper Volume 16, Issue 3 pp 2736—2752

Figure 7. The tumorigenic effect of miR-877-5p in CC can be reversed by KRAS. Si-NC+inhibitor-NC, si-NC+miR-877-5p-inhibitor, si-KRAS+inhibitor-NC, and si-KRAS+miR-877-5p-inhibitor were co-transfected in CaSki cells. (A, B) qRT-PCR measurement of KRAS and miR-877-5p levels. (C–G) CCK-8, EdU, and colony formation assays measuring cell proliferation. (H–K) Wound-healing assays assessing cell migration and Transwell assays measuring cell invasion. P < 0.05, ^**P < 0.01, ^***P < 0.001.