Research Paper Volume 16, Issue 3 pp 2736—2752

circ_0039787 promotes cervical cancer cell tumorigenesis by regulation of the miR-877-5p-KRAS axis

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Figure 5. Reversal of carcinogenic effects of circ_0039787 by miR-877-5p. PCD25+miR-NC, PCD25+miR-877-5p mimics, PCD25-circ_0039787+miR-NC, PCD25-circ_0039787+miR-877-5p mimics in co-transfected HeLa cells. (A, B) circ_0039787 and miR-877-5p mRNA levels. (CG) CCK-8, EdU, and colony formation assays for measuring cell proliferation. (H, I) Wound-healing assays assessing migration. (J, K) Transwell assay measuring cell invasion. P < 0.05, **P < 0.01, ***P < 0.001.