Research Paper Volume 16, Issue 3 pp 2638—2656
Serum metabolome and gut microbiome alterations are associated with low handgrip strength in older adults
Figure 2. Serum metabolomics analysis. (A) PLS-DA analysis of the grouped discrimination by the first two principal components (PCs) in negative and positive ion modes. (B) Pie graph of the class composition according to the number of altered metabolites. (C) Bubble chart of the pathway enrichment analysis of differential metabolites analyzed in the negative- and positive-ion modes. RichFactor was the number of differential metabolites divided by the identified metabolites annotated to the pathway.