Research Paper Volume 16, Issue 3 pp 2475—2493

KLF3 promotes colorectal cancer growth by activating WNT1

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Figure 2. KLF3 expression is associated with proliferation in CRC cells. (AD) The efficacy of knockdown and oe-KLF3 in HCT116 and SW480 CRC cells were evaluated. (EO) Inhibition and promotion of cellular proliferation induced by KLF3 overexpression and knockdown, respectively, shown by CCK-8, EdU, and colony formation assays. Scale bars: 50 μm. *P<0.05, **P<0.01, ***P< 0.001.