Figure 2. KLF3 expression is associated with proliferation in CRC cells. (A–D) The efficacy of knockdown and oe-KLF3 in HCT116 and SW480 CRC cells were evaluated. (E–O) Inhibition and promotion of cellular proliferation induced by KLF3 overexpression and knockdown, respectively, shown by CCK-8, EdU, and colony formation assays. Scale bars: 50 μm. *P<0.05, **P<0.01, ***P< 0.001.