Research Paper Volume 16, Issue 3 pp 2385—2397

Ethanol extract of Evodia lepta Merr. ameliorates cognitive impairment through inhibiting NLRP3 inflammasome in scopolamine-treated mice

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Figure 2. Evodia lepta extract improves cognitive impairment (Morris Water Maze) in scopolamine-treated mice. (A) Escape latency measured as mean time (s) during the navigation test. (B) Representative swim traces of each group. (C) Times of crossing the target platform in the probe trial. (D) Time spent in the target quadrant in the probe trial. (E) The swimming speed in the probe trial. Evodia lepta 10 (10 mg/kg/d); Evodia lepta 20 (20 mg/kg/d). Data represent mean ± SD (n = 10 per group). ##P < 0.01, vs. Control; *P < 0.05, **P < 0.01, ***P < 0.001, vs. SCOP.