Research Paper Volume 16, Issue 3 pp 2362—2384

Prepared Radix Polygoni Multiflori and emodin alleviate lipid droplet accumulation in nonalcoholic fatty liver disease through MAPK signaling pathway inhibition

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Figure 6. PRPM mediates the AMPK signaling pathway in NAFLD. (A) IHC staining of SREBP-1, ×200, ×400. (B) A correlation analysis of the H-scores of SREBP-1. (C) Representative Western blot of SREBP-1, ACC1, FASN, and ACLY. (DG) Western blot analysis. (HK) Relative mRNA levels of SREBP-1, ACC1, FASN, and ACLY (ratio: measured mRNA/GAPDH mRNA). *indicates comparison with NC, P < 0.05. #indicates a comparison with NAFLD, P < 0.05. The white line indicates 50 μm.