Research Paper Volume 16, Issue 3 pp 2362—2384
Prepared Radix Polygoni Multiflori and emodin alleviate lipid droplet accumulation in nonalcoholic fatty liver disease through MAPK signaling pathway inhibition
Figure 1. Enrichment analysis of the anti-NAFLD mechanisms of PRPM. (A) Sixty-six common targets of NAFLD and PRPM. (B) The top 10 significantly enriched (p < 0.05) terms in BP, CC and MF of GO analysis. The Y-axis represents the enrichment count of the target, and the X-axis represents the GO category of the target gene. (C) The top 15 pathways with significant enrichment (p < 0.05) were selected. The Y-axis represents the pathway, while the colors represent the significance of differential enrichment, and the size of the circles represents the number of genes. (D) Ingredient-target-pathway network of PRPM. The red rhombuses indicate ingredients, the green circles indicate targets, and the orange rounded rectangle indicates pathways.