Research Paper Volume 16, Issue 3 pp 2340—2361
5-methylcytosine RNA modification regulators-based patterns and features of immune microenvironment in acute myeloid leukemia
Figure 4. Genetic alterations of m5C regulators in acute myeloid leukemia (AML). (A) Mutation analysis of m5C regulators in AML patients. (B) Alteration frequency of m5C regulators and DNMT3A. (C) The peripheral blood smears of two AML patients. (D) Kaplan–Meier curves showing the overall survival of AML patients with DNMT3A mutations. (E) Homozygous and heterozygous CNV analysis of m5C regulators in AML patients. (F) Pearson correlation analysis between CNV and mRNA expression of m5C regulators. (G) Association between overall survival and deletions in m5C regulators in AML patients.