Research Paper Volume 16, Issue 2 pp 1938—1951
Long noncoding RNA MEG3 regulates cell proliferation and apoptosis by disrupting microRNA-9-5p-mediated inhibition of NDRG1 in prostate cancer
Figure 4. NDRG1 is a downstream target of miR-9-5p. (A) Schematic of the predicted miR-9-5p binding site on NDRG1. (B) Luciferase activity of wild type or mutated NDRG1 in 293T cells after cotransfection with miR-9-5p. (C) Western blot analysis showed that regulation of miR-9-5p could affect the expression of NDRG1. (D) Negative correlation between the expression of miR-9-5p and NDRG1 in 20 PCa tissues analyzed by qPCR, * P < 0.05.