Research Paper Volume 16, Issue 2 pp 1750—1766

Development and validation of glycosyltransferase related-gene for the diagnosis and prognosis of head and neck squamous cell carcinoma

class="figure-viewer-img"

Figure 5. Correlation of tumor microenvironment (TME) landscape and ICI therapy with risk score. (A) The proportions of TME cells in high- and low-risk groups. Significant statistical differences between the two subgroups were assessed using the Wilcoxon test. (B) Linear regression among immune checkpoints (CTLA4, FAP, ICOS, LOXL2, and PDCD1) and risk scores, and the numbers placed on the right of the plot represent coefficients. (C) TIDE, MSI, and T cell exclusion and dysfunction score in two groups. (*p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001).