Research Paper Volume 16, Issue 2 pp 1440—1462

Identification and validation of SLCO4C1 as a biological marker in hepatocellular carcinoma based on anoikis classification features

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Figure 4. Enrichment analysis and prognostic model construction based on anoikis DEGs. (AC) GO pathways enriched between the high-risk and low-risk groups. (D) KEGG pathways enriched between high-risk and low-risk groups. (EG) ROC curves of all samples, train group and test group. (H, I) Univariate and multivariate Cox regression analysis showed that the risk score based on anoikis correlation cluster was an independent prognostic factor affecting the prognosis of HCC patients. (J) There are significant differences between cluster A and cluster B in risk score. (K) The ROC prediction curve of the anoikis model. (L) Sankey diagram reveals the potential relationship between clustering, risk score and survival status.