Research Paper Volume 16, Issue 2 pp 1399—1413

Identification of CD8+ T cell-related biomarkers and immune infiltration characteristic of rheumatoid arthritis

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Figure 2. Development of WGCNA to identify the gene modules most correlated with immune cells in RA. (A) Cluster analysis of samples. (B) Construction of a scale free network with a soft threshold (β) set to 4. (C) Identification of gene modules based on dynamic tree cutting. (D) Correlation analysis of gene expression between different gene modules. (E) Correlation analysis of gene modules and 23 types of immune cells. Blue represents negative correlation and red represents positive correlation. (F) Association between module members and gene significance.