Research Paper Volume 16, Issue 2 pp 1390—1398

Figure 1. GAN inhibited the IL-4-induced macrophage M2 polarization. (A–C) M1 macrophage markers (n = 3). TNF-α, IL-1β and IFN-γ levels in RAW264.7 differed insignificantly from those in J774A.1. (D–F) M2 macrophage markers (n = 3). GAN could inhibit the expressions of IL-10, TGF-β and Arg-1, showing significant differences from the IL-4 group. (G, H) Relative protein expressions (n = 3). Although GAN inhibited the p-STAT6 expression. ^*P < 0.05 vs. DMSO; ^#P < 0.05 vs. IL-4.