Research Paper Volume 16, Issue 2 pp 1318—1335
Long non-coding RNA MEG3 acts as a suppressor in breast cancer by regulating miR-330/CNN1
Figure 1. Prediction and validation of a ceRNA network consisting miR-330, lncRNA MEG3, and CNN1. (A) A ceRNA network composed of lncRNA MEG3, miR-330, CNN1 and ARHGAP20. (B) Gene expression of lncRNA MEG3, miR-330, CNN1 and ARHGAP20 of tumor and normal samples in TCGA. (C) Correlation analysis was performed between expression levels of lncRNA MEG3, miR-330, and CNN1. (D) Overall survival time was significantly different between high expression samples and low expression samples of lncRNA MEG3, miR-330, and CNN1. Abbreviation: PCC: Pearson correlation coefficient.