Research Paper Volume 15, Issue 24 pp 15557—15577

Exploring the effect and mechanism of Aloin A against cancer cachexia-induced muscle atrophy via network pharmacology, molecular docking, molecular dynamics and experimental validation

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Figure 9. Effect of Aloin A on muscle dysfunctional behavior in mice bearing lung tumor. (A) Study design. (B) Rotarod time on rotarod test. (C) Four paws hanging time on inverted screen test. (D) Fore-limb hanging time on wire grip test. (E) Frailty score on wire grip test. The values are shown as the mean ± SEM (n = 8). ***P < 0.001 vs. the control group. #P < 0.05, ##P < 0.01 vs. the LLC group.