Figure 12 — Exploring the effect and mechanism of Aloin A against cancer cachexia-induced muscle atrophy via network pharmacology, molecular docking, molecular dynamics and experimental validation

Research Paper|Volume 15, Issue 24|pp. 15557–15577

Exploring the effect and mechanism of Aloin A against cancer cachexia-induced muscle atrophy via network pharmacology, molecular docking, molecular dynamics and experimental validation

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Figure 12.Effect of Aloin A on mRNA expression of HSP90AA1, AKT1 and AKT3 and in skeletal muscle of mice. (A) mRNA expression of HAP90AA1. (B) mRNA expression ratio of AKT1. (C) mRNA expression of AKT3. The values are shown as the mean ± SEM (n = 6). ^**P < 0.01 vs. the control group. ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 vs. the LLC group.