Research Paper Volume 15, Issue 24 pp 15504—15524

Comprehensively prognostic and immunological analysis of VRK Serine/Threonine Kinase 1 in pan-cancer and identification in hepatocellular carcinoma

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Figure 9. VRK1 promotes HCC cell proliferation and invasion. (A) The protein and mRNA expression levels of VRK1 in HCC cells after transfection with shVRK1 or shNC. (B) Statistical plots and representative images of the wound healing assay in HCC cells transfected with shVRK1. (C) Representative images and quantification of Edu assay in HCC cells transfected with shVRK1. (D) Colony formation assays detecting the cell proliferation in HCC cells transfected with shVRK1. (E) Transwell assays show the suppressed migration and invasion ability of HCC cells transfected with shVRK1 (*P < 0.05, **P < 0.01, and ***P < 0.001).