Research Paper Volume 16, Issue 2 pp 1161—1181

A circRNA ceRNA network involved in cognitive dysfunction after chronic cerebral hypoperfusion

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Figure 8. CCH induces the loss of synapses and increased phagocytosis of synapses by microglia. (A) Brain slices of the hippocampus were stained with synapsin and PSD95 antibodies to show the synapses. (B) The density of synapses was analyzed (n=5). (C) Brain slices of the hippocampus were stained with PSD-95 and IBA-1 antibodies to show the engulfing of synapses by microglia. (D) The PSD-95 positive punctation number of microglia’s cell body was analyzed (n=6). Scale bar = 2.5μm.