Research Paper Volume 16, Issue 2 pp 1096—1110
TRPV1 modulated NLRP3 inflammasome activation via calcium in experimental subarachnoid hemorrhage
Figure 5. Effect of NLRP3 on TRPV1 mediated neurological dysfunction and inflammatory response at 24 h post SAH. (A, B) Neurological function was valued via modified Garcia and beam score. (C) The water content of the left hemisphere. (D) The protein level of IL-1β was assessed via ELISA. (E–I) The mRNA level of CD16, CD32, CD86, IL-1β, and TNF-α in brain tissues was assessed via qPCR. Abbreviation: no significance; *p < 0.05, **p < 0.01 and ****p < 0.0001.