Research Paper Volume 15, Issue 24 pp 15451—15472

Identification and validation of key biomarkers associated with macrophages in nonalcoholic fatty liver disease based on hdWGCNA and machine learning

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Figure 7. Verification of expression and diagnostic efficacy for optimal feature genes. (A) MAFB and CX3CR1 mRNA expression in the training group. (B) ROC curves of MAFB and CX3CR1 in the training group. (C) MAFB and CX3CR1 mRNA expression in the testing group. (D) ROC curves of MAFB and CX3CR1 in the testing group. (E) Correlation analysis between MAFB and CX3CR1. (F) Heatmap showing the scores of KEGG pathways in the optimal feature genes as calculated by GSVA. (G) Heatmap showing the correlation between the gene pathway and optimal feature genes. *P < 0.05, **P < 0.01, ***P < 0.001.