Research Paper Volume 16, Issue 2 pp 1077—1095

Establishing the role of BRCA1 in the diagnosis, prognosis and immune infiltrates of breast invasive cancer by bioinformatics analysis and experimental validation

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Figure 7. DNA promoter methylation level of BRCA1 and its effect on prognosis of patients with BRCA. (A) The promoter methylation level of BRCA1 in BRCA was lower than that in normal breast tissue. (B) Correlation between BRCA1 mRNA expression level and methylation level. (C) KM survival curves for methylation sites of BRCA1. P-values were calculated with two-tailed unpaired Student’s t-test, *p < 0.05, **p < 0.01, ***p < 0.001.