Research Paper Volume 15, Issue 24 pp 15360—15381

Clinical and therapeutical significances of the cluster and signature based on oxidative stress for osteosarcoma

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Figure 3. Establishment of OXS-signature for TARGET-OS. (A) Forest plot for Univariate Cox regression analysis of 18 prognostic genes 125 differentially expressed genes between the two OXS-clusters; (B) The distribution of error rates in Random Survival Forest model and the variable relative importance of the six genes. Notably, only genes with variable importance greater than 0.3 were screened out for display. (C) Lambda selection diagram for Least Absolute Shrinkage and Selection Operator (LASSO) analysis, with different colored curves representing different genes.