Clinical and therapeutical significances of the cluster and signature based on oxidative stress for osteosarcoma

Mengjie Ding; Xianting Ran; Siyu Qian; Yue Zhang; Zeyuan Wang; Meng Dong; Zhenzhen Yang; Shaoxuan Wu; Xiaoyan Feng; Jieming Zhang; Linan Zhu; Songtao Niu; Xudong Zhang

doi:doi:10.18632/aging.205354

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Research Paper Volume 15, Issue 24 pp 15360—15381

Clinical and therapeutical significances of the cluster and signature based on oxidative stress for osteosarcoma

Figure 2. Enrichment analysis of OXS-clusters in TARGET-OS. (A) GSEA maps of cancer and immune-related signaling pathways for OXS-clusters; (B) The volcano map reflecting the differentially expressed genes identified between the two OXS-clusters (logFC>1, FDR<0.01), with the black dots representing genes that do not reach the threshold, and the red dots representing genes that reach the threshold; (C) KEGG enrichment map of 125 differentially expressed genes.