Research Paper Volume 15, Issue 24 pp 15287—15323
Integrated analysis of bulk RNA-seq and single-cell RNA-seq reveals the function of pyrocytosis in the pathogenesis of abdominal aortic aneurysm
Figure 2. Pyroptosis-related gene expression in AAA Combined Datasets. (A) Venn diagram of pyroptosis-related genes and DEGs. (B) Chromosomal mapping of pyroptosis-related genes from overlapping genes. (C) Box plot of pyroptosis-related genes expression in the AAA and Con groups. (D) Heatmap of pyroptosis-related in combined GEO Datasets. *P < 0.05, P < 0.01, ***P < 0.001, the red represents positive correlation, blue represents the negative correlation. Scatter plot of the correlation between CHMP2B and CHMP4A (E), IL-1β and NLRP3 (F), IL-18 and GSDMB (G), IL-6 and GPX4 (H), CASP6 and GSDMC (I), and CHMP4A and NLRP7 (J) in AAA Combined Datasets. Abbreviations: AAA: Abdominal aortic aneurysm; CON: Control; DEG: differential gene expression.