Research Paper Volume 15, Issue 24 pp 15183—15195

Inhibition of TGF-β1-induced epithelial-mesenchymal transition in gliomas by DMC-HA

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Figure 4. Effects of DMC-HA on the Akt and Erk signalling in glioma cells. (A) Western blot analysis was conducted to assess the expression of p-Akt and p-mTor following combined treatment with TGF-β1 and DMC-HA. (B) Western blot analysis was conducted to assess the expression of N-cadherin and ZO-1 following combined treatment with TGF-β1 and LY294002. (C) Western blot analysis was conducted to assess the expression of p-Erk1/2 following combined treatment with TGF-β1 and DMC-HA. (D) Western blot analysis was conducted to assess the expression of N-cadherin and ZO-1 following combined treatment with TGF-β1 and SCH 772984.